What Is HEMA and HPMA in Gel Polish? Ingredient Guide for Nail Professionals
As ingredient safety becomes a growing concern in the nail and cosmetic industry, two acrylate monomers have come under increasing scrutiny: HEMA and HPMA. Commonly used in gel nail polish, base gels, and builder gels, HEMA (2-Hydroxyethyl Methacrylate) and HPMA (Hydroxypropyl Methacrylate) both play vital roles in adhesion and product performance. But what are they exactly — and are they safe? This article breaks down their definitions, differences, uses, and regulatory concerns to help brands, nail technicians, and consumers make more informed decisions.
、What Is HEMA?
HEMA stands for 2-Hydroxyethyl Methacrylate. It is a low-viscosity monomer that improves adhesion between the natural nail and the gel product. It is one of the most widely used ingredients in UV/LED gel systems, including:
-
Base coats
-
Builder gels
-
Soak-off gel polishes
-
Acrylic nail liquids
HEMA helps gel products bond tightly to the nail plate and enhances flexibility and durability. However, HEMA is also known as a high-sensitizing allergen, especially in uncured or undercured form.
Potential Concerns:
-
May cause skin irritation or allergic contact dermatitis
-
Classified as a skin sensitizer under the EU CLP Regulation
-
Subject to ingredient concentration restrictions in the EU (typically ≤ 35% in finished products)
-
Often banned or discouraged in “HEMA-free” formulations for sensitive users
—
2、What Is HPMA?
HPMA stands for Hydroxypropyl Methacrylate. It is another methacrylate monomer with similar properties to HEMA but is generally considered to be less sensitizing.
HPMA is used as:
-
An alternative to HEMA in low-sensitivity gel systems
-
A diluent and adhesion promoter in gel and acrylic formulas
-
A key component in HEMA-free or hypoallergenic nail products
Compared to HEMA, HPMA offers a better safety profile and is less likely to trigger allergic reactions, making it a preferred choice in “sensitive skin” gel formulations.
—
HEMA vs. HPMA: Key Differences
Feature | HEMA | HPMA |
---|---|---|
Full Name | 2-Hydroxyethyl Methacrylate | Hydroxypropyl Methacrylate |
Main Use | Adhesion promoter in gel systems | Adhesion and HEMA substitute |
Viscosity | Lower (more fluid) | Slightly higher than HEMA |
Allergen Risk | Higher – skin sensitizer | Lower – more suitable for sensitive skin |
EU Regulations | Restricted use (≤35% in final product) | Not banned, but still regulated |
Used In | Base gel, builder gel, acrylic systems | HEMA-free gel polish, soft gels |
3、Are HEMA and HPMA Safe?
Both HEMA and HPMA are safe when used correctly in professional-grade, fully cured nail products. However, improper application (e.g., skin contact, under-curing, overuse) can increase the risk of sensitization, especially with HEMA.
To ensure safety:
-
Avoid skin contact during application
-
Fully cure under recommended UV/LED light time
-
Choose “HEMA-free” products if you or your clients are allergy-prone
-
Wear gloves and work in a well-ventilated area when using professional products
4、The Rise of HEMA-Free Products
As consumer awareness increases and EU cosmetic regulations evolve, more brands are offering HEMA-free and HPMA-based gel polish lines. These alternatives help reduce the risk of allergic reactions while still offering excellent adhesion and wear time.
Ideal for:
-
Sensitive or allergy-prone users
-
Brands exporting to markets with stricter safety standards
-
Professionals seeking safer, low-irritant options for clients
—
HEMA and HPMA are foundational ingredients in modern gel polish systems. While HEMA offers strong adhesion, it comes with a higher allergy risk, making HPMA a safer, increasingly popular substitute. Nail brands and professionals should carefully evaluate which monomers align with their product goals, market requirements, and client sensitivities.

How to Heal Damaged Cuticles: Your 5-Step Guide to Pain-Free Nail Care

Long-Term Nail Health: How HEMA-Free Gel Nail Polish Protects Against Damage

How to Get No Bubbles with Magic Poke Gel: A Pro's Ultimate Guide

Dip vs. Acrylic Nails: Which is Healthier for Your Natural Nails?

TPO-Free Cat Eye Gel for Sensitive Skin: The Ultimate Guide to Safe Christmas Nails
FAQ
Can I customize the formula and colors?
Absolutely! We offer full customization, including formula, color shades, textures, and finishes to match your brand’s vision.
How can I place an order?
Simply contact us with your requirements, and our team will guide you through the customization, production, and shipping process.
For After-sales
What can I do if the gel nail polish colors don't match what l purchased?
If you think you have received the wrong set you ordered, please contact our customer support team and we will get back to yousoon.lf it is the corect product but you are unsatisfied with the color match, we work very hard to closely match each color to adigital replication for our image. lt is impossible to match an exact color with any digitalrepresentation of a physical product;however, we have worked closely on each set making sure that each color is as close as it can be to the color in the bottle.lfyou arestill unsatisfied, please contact us. We are here to help and make it right in any way!
For Products
Are your products cruelty free?
Absolutely, we love our fur babies! All of our products are cruelty-free! Beauty without cruelty is something we strongly believe in and the only guinea pigs we test on is our willing team of Hanyi staff!
HEMA-Free Gel Polish
What does "HEMA-Free" mean?
HEMA-free gel polishes are formulated without Hydroxyethyl Methacrylate, a common allergen in traditional gels. They use alternative bonding agents that are gentler on skin while still providing long-lasting wear.
Recommended for You

🔑 Key Features:
-
🌸 Vibrant Pitaya Pink Color—Trendy and bold, perfect for all skin tones and seasons.
-
💅 Long-Lasting Formula—Stays chip-free for up to 21 days with proper application.
-
✨ High Gloss Finish—Provides a salon-quality shine that won't dull.
-
🌿 Eco-Friendly & Cruelty-Free – Made with non-toxic ingredients, gentle on nails.
-
🛠️ OEM/ODM Support—Customize color, packaging, logo, bottle shape, and more.
-

✨ Key Features:
✔ 100% HEMA-Free Formula—Gentle on nails and skin, ideal for sensitive users and allergy-prone customers.
✔ Vegan & Organic—Cruelty-free, eco-conscious, and skin-friendly.
✔ Vibrant Colors & Pigmentation—Rich, full-coverage colors with intense pigment that require only a thin layer for bold results.
✔ Quick & Easy Application—Smooth consistency that applies evenly for professional-looking results at home or in the salon.
✔ Safe for Sensitive Skin—Formulated without harmful chemicals and safe for most nail types, including sensitive skin.
✔ OEM/ODM Support—From formula tweaks to bulk orders, we bring your brand to life.
Ideal for salons, indie brands, and retailers who value safety, sustainability, and standout style.
"Get vibrant, long-lasting color—unlock creativity with Pat Pat Gel ."

✨ Key Features:
✔ 100% HEMA-Free Formula—Gentle on nails and skin, ideal for sensitive users and allergy-prone customers.
✔ Vegan & Organic—Cruelty-free, eco-conscious, and skin-friendly.
✔ No-Wipe Formula—The finish leaves no sticky layer, eliminating the need for additional top coats or wipe-off solutions.
✔ Vibrant Colors & Pigmentation—Rich, full-coverage colors with intense pigment that require only a thin layer for bold results.
✔ Quick & Easy Application—Smooth consistency that applies evenly for professional-looking results at home or in the salon.
✔ Quick & Easy Application—Smooth consistency that applies evenly for professional-looking results at home or in the salon.
✔ Safe for Sensitive Skin—Formulated without harmful chemicals and safe for most nail types, including sensitive skin.
✔ OEM/ODM Support—From formula tweaks to bulk orders, we bring your brand to life.
Ideal for salons, indie brands, and retailers who value safety, sustainability, and standout style.
"Get vibrant, long-lasting color—unlock creativity with Paint Gel."

✨ Key Features:
✔ Vegan & Organic—Cruelty-free, eco-conscious, and skin-friendly.
✔ Deep Moisturizing Formula—Softens dry, cracked cuticles and nourishes surrounding skin
✔ Promotes Healthy Nail Growth—Supports stronger, longer nails with regular use
✔ Natural & Plant-Based Oils—Infused with ingredients like Vitamin E, Jojoba, and Sweet Almond Oil
✔ Non-Greasy & Fast-Absorbing – Leaves no residue; perfect for daily use or on-the-go hydration
✔ Lightweight & Refreshing Scent – Gentle floral or fruity aroma adds a spa-like touch to your nail routine
✔ Perfect for At-Home or salon use—great for professional manicures or personal nail care routines
✔ Suitable for All Skin Types—Gentle on sensitive skin, cuticle areas, and nail beds
"Perfect for repairing dry cuticles and promoting healthy nail growth."
Looking for a creative, premium, and reliable nail product manufacturer?
Whether you're an Amazon seller, Shopify store owner, chain store buyer, brand owner, distributor, wholesaler, or nail supply retailer — Hanyinails is your trusted partner for custom and wholesale nail solutions.
Hanyinails
Hanyinails
Hanyinails
Hanyinails